What Is Trinomia

Trinomia is the first polypill composed of three active principles . This medicine is indicated to prevent cardiovascular accidents. The three active principles present in Trinomia are:

• Acetylsalicylic acid
• Atorvastatin
• Ramipril

This medicine is indicated to replace the established treatment in patients who are taking all three components at the same time. The doses that are normally used are those that are needed so that the risk of experiencing a cardiovascular accident is lower. Especially in cases where one has previously been suffered. 

Composition of Trinomia

Trinomia capsules contain three different active ingredients, each of which has an effect on cardiovascular risk factors.

• Acetylsalicylic acid: p It belongs to the group of antiplatelet drugs. It works by preventing platelets from clumping together and forming a clot.
• Atorvastatin: e It is an active substance that belongs to the group of statins. These are drugs that help regulate cholesterol and triglyceride levels in the blood. 
• Ramipril: and Ramipril belongs to the group of medicines that are ACE (angiotensin converting enzyme) inhibitors. This active principle exerts its effect on blood vessels by controlling blood pressure. Its mechanism of action produces a relaxation of the blood vessels leading to an increase in their diameter. Thanks to this effect, the heart pumps blood to the rest of the body more easily.

How to take Trinomia

The doctor will be the one to tell you how to start treatment with Trinomia. Although in general, the usual dose is one capsule a day after dinner. Trinomia capsules should not be opened, crushed or chewed. 

Treatment cannot be abruptly abandoned without first talking to the doctor, since it is a medicine indicated for patients at risk who have previously experienced a cardiovascular accident.

Possible side effects

Trinomia, like all medicines, can cause adverse effects.   However, you should stop treatment if you experience serious side effects, including the following:

• Vomiting blood : This symptom is important as it is a sign of a stomach bleeding.
• Allergic reactions: of the skin, the respiratory tract, especially in asthmatic patients.
• Serious hemorrhages: among which is cerebral hemorrhage, especially if your blood pressure is high and is not controlled and also in case you are on anticoagulant treatment.
• Muscle pain or cramps
• Hypersensitivity reactions: if you are hypersensitive to any of the components of Trinomia, you may suffer symptoms such as swelling of the face, tongue and throat, difficulty breathing or swallowing.
• Skin rash: in these cases, reddish spots may appear, especially on the palms of the hands or the soles of the feet, and that can evolve to become  blisters.

Some interactions

Trinomy with food, drink and alcohol

While you are in treatment with this medicine, it is advisable that you do not drink alcohol. Alcohol increases the risk of stomach and intestinal bleeding and ulcers. In addition, alcohol consumption can enhance the effect of some medications used to treat high blood pressure. 

Can I take Trinomia if I am pregnant or breastfeeding?

In the event that you are pregnant you should not take Trinomia, nor if you think you could be. However, if you become pregnant while being treated with this drug, you should stop the treatment and contact your doctor.

However, in the event that you are planning a pregnancy, you will have to change the treatment to an alternative one appropriate to your condition. You should also not take Trinomia if you are breastfeeding, and in general, l he women of childbearing potential must use effective contraception for the duration of treatment.

The novelty that Trinomia means

With Trinomia it is easier for patients who need secondary prevention to correctly follow the treatment when they leave the hospital.   However, it should not be used in cases where the use of aspirin, ACEIs or statins at medium or high doses is contraindicated.